param_typeOfDesign

<p>The type of design. Type of design is one of the following: 
O'Brien &amp; Fleming (<code>"OF"</code>), Pocock (<code>"P"</code>), Wang &amp; Tsiatis Delta class (<code>"WT"</code>), 
Pampallona &amp; Tsiatis (<code>"PT"</code>),
Haybittle &amp; Peto ("HP"), Optimum design within Wang &amp; Tsiatis class (<code>"WToptimum"</code>), 
O'Brien &amp; Fleming type alpha spending (<code>"asOF"</code>), Pocock type alpha spending (<code>"asP"</code>), 
Kim &amp; DeMets alpha spending (<code>"asKD"</code>), Hwang, Shi &amp; DeCani alpha spending (<code>"asHSD"</code>), 
user defined alpha spending (<code>"asUser"</code>), default is <code>"OF"</code>.</p>

typeOfDesign

<p>Parameter Description: Type of Design</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_typeOfDesign: Parameter Description: Type of Design

Description

Arguments