param_adaptations

A vector of length <code>kMax - 1</code> indicating whether or not an adaptation takes 
place at interim k, default is <code>rep(TRUE, kMax - 1)</code>.

adaptations

Parameter Description: Adaptations

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

param_adaptations function

<dl><dt>adaptations</dt>
<dd>A vector of length <code>kMax - 1</code> indicating whether or not an adaptation takes 
place at interim k, default is <code>rep(TRUE, kMax - 1)</code>.</dd></dl>

Arguments

Parameter Description: Adaptations — param_adaptations

<dl>

<dt>adaptations</dt>
<dd>A vector of length <code>kMax - 1</code> indicating whether or not an adaptation takes 
place at interim k, default is <code>rep(TRUE, kMax - 1)</code>.</dd>

</dl>