param_design_with_default

Parameter Description: Design with Default

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

param_design_with_default function

<dl><dt>design</dt>
<dd>The trial design. If no trial design is specified, a fixed sample size design is used.
In this case, Type I error rate <code>alpha</code>, Type II error rate <code>beta</code>, <code>twoSidedPower</code>,
and <code>sided</code> can be directly entered as argument where necessary.</dd></dl>

Arguments

Parameter Description: Design with Default — param_design_with_default

<dl>

<dt>design</dt>
<dd>The trial design. If no trial design is specified, a fixed sample size design is used.
In this case, Type I error rate <code>alpha</code>, Type II error rate <code>beta</code>, <code>twoSidedPower</code>,
and <code>sided</code> can be directly entered as argument where necessary.</dd>

</dl>