param_intersectionTest_Enrichment

Parameter Description: Intersection Test

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

param_intersectionTest_Enrichment function

<dl><dt>intersectionTest</dt>
<dd>Defines the multiple test for the intersection
hypotheses in the closed system of hypotheses.
Four options are available in enrichment designs: <code>"SpiessensDebois"</code>, <code>"Bonferroni"</code>, <code>"Simes"</code>,
and <code>"Sidak"</code>, default is <code>"Simes"</code>.</dd></dl>

Arguments

Parameter Description: Intersection Test — param_intersectionTest_Enrichment

<dl>

<dt>intersectionTest</dt>
<dd>Defines the multiple test for the intersection
hypotheses in the closed system of hypotheses.
Four options are available in enrichment designs: <code>"SpiessensDebois"</code>, <code>"Bonferroni"</code>, <code>"Simes"</code>,
and <code>"Sidak"</code>, default is <code>"Simes"</code>.</dd>

</dl>