param_minNumberOfEventsPerStage

Parameter Description: Min Number Of Events Per Stage

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

param_minNumberOfEventsPerStage function

<dl><dt>minNumberOfEventsPerStage</dt>
<dd>When performing a data driven sample size recalculation,
the numeric vector <code>minNumberOfEventsPerStage</code> with length kMax determines the
minimum number of events per stage (i.e., not cumulated), the first element
is not taken into account.</dd></dl>

Arguments

Parameter Description: Min Number Of Events Per Stage — param_minNumberOfEventsPerStage

<dl>

<dt>minNumberOfEventsPerStage</dt>
<dd>When performing a data driven sample size recalculation,
the numeric vector <code>minNumberOfEventsPerStage</code> with length kMax determines the
minimum number of events per stage (i.e., not cumulated), the first element
is not taken into account.</dd>

</dl>