param_slope

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

param_slope function

<dl><dt>slope</dt>
<dd>If <code>typeOfShape = "sigmoidEmax"</code> is selected, <code>"slope"</code> can be entered
to specify the slope of the sigmoid Emax model, default is 1.</dd></dl>

Arguments

Parameter Description: Slope — param_slope

<dl>

<dt>slope</dt>
<dd>If <code>typeOfShape = "sigmoidEmax"</code> is selected, <code>"slope"</code> can be entered
to specify the slope of the sigmoid Emax model, default is 1.</dd>

</dl>

Parameter Description: Slope