param_typeOfSelection

Parameter Description: Type of Selection

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

param_typeOfSelection function

<dl><dt>typeOfSelection</dt>
<dd>The way the treatment arms or populations are selected at interim.
Five options are available: <code>"best"</code>, <code>"rbest"</code>, <code>"epsilon"</code>, <code>"all"</code>, and <code>"userDefined"</code>,
default is <code>"best"</code>. 
For <code>"rbest"</code> (select the <code>rValue</code> best treatment arms/populations), the parameter <code>rValue</code> has to be specified,
for <code>"epsilon"</code> (select treatment arm/population not worse than epsilon compared to the best), the parameter
<code>epsilonValue</code> has to be specified.
If <code>"userDefined"</code> is selected, <code>"selectArmsFunction"</code> or <code>"selectPopulationsFunction"</code> has to be specified.</dd></dl>

Arguments

Parameter Description: Type of Selection — param_typeOfSelection

<dl>

<dt>typeOfSelection</dt>
<dd>The way the treatment arms or populations are selected at interim.
Five options are available: <code>"best"</code>, <code>"rbest"</code>, <code>"epsilon"</code>, <code>"all"</code>, and <code>"userDefined"</code>,
default is <code>"best"</code>. 
For <code>"rbest"</code> (select the <code>rValue</code> best treatment arms/populations), the parameter <code>rValue</code> has to be specified,
for <code>"epsilon"</code> (select treatment arm/population not worse than epsilon compared to the best), the parameter
<code>epsilonValue</code> has to be specified.
If <code>"userDefined"</code> is selected, <code>"selectArmsFunction"</code> or <code>"selectPopulationsFunction"</code> has to be specified.</dd>

</dl>