param_lambda2

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

Tobias Muetze

param_lambda2 function

<dl><dt>lambda2</dt>
<dd>The assumed hazard rate in the reference group, there is no default.
<code>lambda2</code> can also be used to define piecewise exponentially distributed survival times (see details). Must be a positive numeric of length 1.</dd></dl>

Arguments

Parameter Description: Lambda (2) — param_lambda2

<dl>

<dt>lambda2</dt>
<dd>The assumed hazard rate in the reference group, there is no default.
<code>lambda2</code> can also be used to define piecewise exponentially distributed survival times (see details). Must be a positive numeric of length 1.</dd>

</dl>

Parameter Description: Lambda (2)