param_maxNumberOfSubjects_survival

Parameter Description: Maximum Number Of Subjects For Survival Endpoint

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

Tobias Muetze

param_maxNumberOfSubjects_survival function

<dl><dt>maxNumberOfSubjects</dt>
<dd><code>maxNumberOfSubjects &gt; 0</code> needs to be specified.
If accrual time and accrual intensity are specified, this will be calculated. Must be a positive integer of length 1.</dd></dl>

Arguments

Parameter Description: Maximum Number Of Subjects For Survival Endpoint — param_maxNumberOfSubjects_survival

<dl>

<dt>maxNumberOfSubjects</dt>
<dd><code>maxNumberOfSubjects &gt; 0</code> needs to be specified.
If accrual time and accrual intensity are specified, this will be calculated. Must be a positive integer of length 1.</dd>

</dl>