param_pi1_rates

Parameter Description: Pi (1) for Rates

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

Tobias Muetze

param_pi1_rates function

<dl><dt>pi1</dt>
<dd>A numeric value or vector that represents the assumed probability in
the active treatment group if two treatment groups
are considered, or the alternative probability for a one treatment group design,
default is <code>seq(0.2, 0.5, 0.1)</code> (power calculations and simulations) or
<code>seq(0.4, 0.6, 0.1)</code> (sample size calculations).</dd></dl>

Arguments

Parameter Description: Pi (1) for Rates — param_pi1_rates

<dl>

<dt>pi1</dt>
<dd>A numeric value or vector that represents the assumed probability in
the active treatment group if two treatment groups
are considered, or the alternative probability for a one treatment group design,
default is <code>seq(0.2, 0.5, 0.1)</code> (power calculations and simulations) or
<code>seq(0.4, 0.6, 0.1)</code> (sample size calculations).</dd>

</dl>