param_selectArmsFunction

Parameter Description: Select Arms Function

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Stephen Schueuerhuis

Tobias Muetze

param_selectArmsFunction function

<dl><dt>selectArmsFunction</dt>
<dd>Optionally, a function can be entered that defines the way of how treatment arms
are selected. This function is allowed to depend on <code>effectVector</code> with length <code>activeArms</code>,
<code>stage</code>, <code>"conditionalPower"</code>, <code>"conditionalCriticalValue"</code>, <code>"plannedSubjects/plannedEvents"</code>,
<code>"allocationRatioPlanned"</code>, <code>"selectedArms"</code>, <code>"thetaH1"</code> (for means and survival), <code>"stDevH1"</code> (for means),
<code>"overallEffects"</code>, and for rates additionally: <code>"piTreatmentsH1"</code>, <code>"piControlH1"</code>, <code>"overallRates"</code>, and
<code>"overallRatesControl"</code>.</dd></dl>

Arguments

Parameter Description: Select Arms Function — param_selectArmsFunction

<dl>

<dt>selectArmsFunction</dt>
<dd>Optionally, a function can be entered that defines the way of how treatment arms
are selected. This function is allowed to depend on <code>effectVector</code> with length <code>activeArms</code>,
<code>stage</code>, <code>"conditionalPower"</code>, <code>"conditionalCriticalValue"</code>, <code>"plannedSubjects/plannedEvents"</code>,
<code>"allocationRatioPlanned"</code>, <code>"selectedArms"</code>, <code>"thetaH1"</code> (for means and survival), <code>"stDevH1"</code> (for means),
<code>"overallEffects"</code>, and for rates additionally: <code>"piTreatmentsH1"</code>, <code>"piControlH1"</code>, <code>"overallRates"</code>, and
<code>"overallRatesControl"</code>.</dd>

</dl>