param_adaptations

Parameter Description: Adaptations

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Daniel Sabanes Bove

Stephen Schueuerhuis

Tobias Muetze

param_adaptations function

<dl><dt>adaptations</dt>
<dd>A logical vector of length <code>kMax - 1</code> indicating whether or not an adaptation takes
place at interim k, default is <code>rep(TRUE, kMax - 1)</code>.</dd></dl>

Arguments

Parameter Description: Adaptations — param_adaptations

<dl>

<dt>adaptations</dt>
<dd>A logical vector of length <code>kMax - 1</code> indicating whether or not an adaptation takes
place at interim k, default is <code>rep(TRUE, kMax - 1)</code>.</dd>

</dl>