param_alternative_simulation

Parameter Description: Alternative for Simulation

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Daniel Sabanes Bove

Stephen Schueuerhuis

Tobias Muetze

param_alternative_simulation function

<dl><dt>alternative</dt>
<dd>The alternative hypothesis value for testing means under which the data is simulated.
This can be a vector of assumed alternatives, default is <code>seq(0, 1, 0.2)</code>.</dd></dl>

Arguments

Parameter Description: Alternative for Simulation — param_alternative_simulation

<dl>

<dt>alternative</dt>
<dd>The alternative hypothesis value for testing means under which the data is simulated.
This can be a vector of assumed alternatives, default is <code>seq(0, 1, 0.2)</code>.</dd>

</dl>

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param_alternative_simulation: Parameter Description: Alternative for Simulation

Description

Arguments