param_maxNumberOfSubjects

Parameter Description: Maximum Number Of Subjects

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Daniel Sabanes Bove

Stephen Schueuerhuis

Tobias Muetze

param_maxNumberOfSubjects function

<dl><dt>maxNumberOfSubjects</dt>
<dd><code>maxNumberOfSubjects &gt; 0</code> needs to be specified for power calculations or calculation
of necessary follow-up (count data). For two treatment arms, it is the maximum number of subjects for both treatment arms.</dd></dl>

Arguments

Parameter Description: Maximum Number Of Subjects — param_maxNumberOfSubjects

<dl>

<dt>maxNumberOfSubjects</dt>
<dd><code>maxNumberOfSubjects &gt; 0</code> needs to be specified for power calculations or calculation
of necessary follow-up (count data). For two treatment arms, it is the maximum number of subjects for both treatment arms.</dd>

</dl>