param_successCriterion

Parameter Description: Success Criterion

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Gernot Wassmer

Till Jensen

Daniel Sabanes Bove

Stephen Schueuerhuis

Tobias Muetze

param_successCriterion function

<dl><dt>successCriterion</dt>
<dd>Defines when the study is stopped for efficacy at interim.
Two options are available: <code>"all"</code> stops the trial
if the efficacy criterion is fulfilled for all selected treatment arms/populations,
<code>"atLeastOne"</code> stops if at least one of the selected treatment arms/populations is shown to be
superior to control at interim, default is <code>"all"</code>.</dd></dl>

Arguments

Parameter Description: Success Criterion — param_successCriterion

<dl>

<dt>successCriterion</dt>
<dd>Defines when the study is stopped for efficacy at interim.
Two options are available: <code>"all"</code> stops the trial
if the efficacy criterion is fulfilled for all selected treatment arms/populations,
<code>"atLeastOne"</code> stops if at least one of the selected treatment arms/populations is shown to be
superior to control at interim, default is <code>"all"</code>.</dd>

</dl>