beta_v_indices

A list of indices for <code>rand.idx</code> in <code>bmiq_norm_450k</code> function.
The input probes must be already filtered and ordered the same way to the
that when we developed our placental epigenetic clock. Run
<code>data(probe_info_450k)</code> and find the required probes in
<code>prob_info_450k$probeID</code>.

dataset

Placental epigenetic clock to estimate aging based on gestational age using DNA methylation levels, so called placental epigenetic clock (PlEC). We developed a PlEC for the 2024 Placental Clock DREAM Challenge (<https://www.synapse.org/Synapse:syn59520082/wiki/628063>). Our PlEC achieved the top performance based on an independent test set. PlEC can be used to identify accelerated/decelerated aging of placenta for understanding placental dysfunction-related conditions, e.g., great obstetrical syndromes including preeclampsia, fetal growth restriction, preterm labor, preterm premature rupture of the membranes, late spontaneous abortion, and placental abruption. Detailed methodologies and examples are documented in our vignette, available at <https://herdiantrisufriyana.github.io/rplec/doc/placental_aging_analysis.html>.

Herdiantri Sufriyana

rplec

Placental Epigenetic Clock to Estimate Aging by DNA Methylation

Emily Chia-Yu Su

beta_v_indices function

A list of 2 elements where each has a length of nfit of 10000:<dl>
<dt>beta1.v</dt>
<dd>An integer indicating the selected indices.</dd><dt>beta2.v</dt>
<dd>An integer indicating the selected indices.</dd>
</dl>

Format

Indices for random beta values — beta_v_indices

A list of 2 elements where each has a length of nfit of 10000:<dl>
<dt>beta1.v</dt>
<dd>An integer indicating the selected indices.</dd>

<dt>beta2.v</dt>
<dd>An integer indicating the selected indices.</dd>


</dl>

beta_v_indices: Indices for random beta values

Description

Usage

Arguments

Format