rvHPDT (version 4.0)

Calling Haplotype-Based and Variant-Based Pedigree Disequilibrium Test for Rare Variants in Pedigrees

Description

To detecting rare variants for binary traits using general pedigrees, the pedigree disequilibrium tests are proposed by collapsing rare haplotypes/variants with/without weights. To run the test, MERLIN is needed in Linux for haplotyping.

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Version

Install

install.packages('rvHPDT')

Monthly Downloads

184

Version

4.0

License

GPL (>= 2)

Maintainer

Wei Guo

Last Published

May 12th, 2022

Functions in rvHPDT (4.0)

rvPDT.test.permu

Variants-based pedigree disequilibrium test for rare variants in pedigrees.

rvPDT.test

Variants-based pedigree disequilibrium test for rare variants in pedigrees.

Calling haplotype-based and variant-based pedigree disequilibrium test for rare variants in pedigrees.

whap.prehap

Prepare haplotype pairs for hPDT tests in pedigree data.

rvPDT.test.sub

Internal function.

convert.factors.to.strings.in.dataframe

Convert data.frame columns from factors to characters