.First.lib

plotnpde

internal

saemix-internal

The SAEMIX package implements the Stochastic Approximation EM algorithm for parameter estimation in (non)linear mixed effects models. The SAEM algorithm: - computes the maximum likelihood estimator of the population parameters, without any approximation of the model (linearisation, quadrature approximation,...), using the Stochastic Approximation Expectation Maximization (SAEM) algorithm, - provides standard errors for the maximum likelihood estimator - estimates the conditional modes, the conditional means and the conditional standard deviations of the individual parameters, using the Hastings-Metropolis algorithm. Several applications of SAEM in agronomy, animal breeding and PKPD analysis have been published by members of the Monolix group (http://group.monolix.org/).

Emmanuelle Comets

saemix

Stochastic Approximation Expectation Maximization (SAEM)
algorithm

saemix-internal function

Internal saemix objects — saemix-internal

Internal saemix objects

saemix-internal: Internal saemix objects

Description

Arguments

Details