scMetaTraj_flow

Estimate local direction vectors pointing toward neighbors with higher
metabolic pseudotime. Intended for visualization only.

Provides a framework for modeling cellular metabolic states and continuous
metabolic trajectories from single-cell RNA-seq data using pathway-level
scoring. Enables lineage-restricted metabolic analysis, metabolic
'pseudotime' inference, module-level trend analysis, and visualization of
metabolic state transitions.

Jinwei Dai

scMetaTraj

Metabolic State Space and Trajectory Analysis for Single-Cell
Data

scMetaTraj_flow function

<dl><dt>emb_pca</dt>
<dd>Matrix (cells x PCs) used for neighborhood definition.</dd>
<dt>emb_umap</dt>
<dd>Matrix (cells x 2) used only for visualization.</dd>
<dt>pseudotime</dt>
<dd>Numeric vector of mPT.</dd>
<dt>k</dt>
<dd>Integer. Number of nearest neighbors.</dd>
<dt>min_delta</dt>
<dd>Minimum mPT difference to consider a neighbor "forward".</dd></dl>

Arguments

Compute local directional consistency along mPT — scMetaTraj_flow

<dl>

<dt>emb_pca</dt>
<dd>Matrix (cells x PCs) used for neighborhood definition.</dd>


<dt>emb_umap</dt>
<dd>Matrix (cells x 2) used only for visualization.</dd>


<dt>pseudotime</dt>
<dd>Numeric vector of mPT.</dd>


<dt>k</dt>
<dd>Integer. Number of nearest neighbors.</dd>


<dt>min_delta</dt>
<dd>Minimum mPT difference to consider a neighbor "forward".</dd>

</dl>

scMetaTraj_flow: Compute local directional consistency along mPT

Description

Usage

Value

Arguments