scMetaTraj_transition_zone

Identify a candidate transition zone along mPT where the composition
of metabolic subclusters changes most rapidly. Intended as a
hypothesis-generating indicator.

Provides a framework for modeling cellular metabolic states and continuous
metabolic trajectories from single-cell RNA-seq data using pathway-level
scoring. Enables lineage-restricted metabolic analysis, metabolic
'pseudotime' inference, module-level trend analysis, and visualization of
metabolic state transitions.

Jinwei Dai

scMetaTraj

Metabolic State Space and Trajectory Analysis for Single-Cell
Data

scMetaTraj_transition_zone function

<dl><dt>mPT</dt>
<dd>Numeric vector of metabolic pseudotime.</dd>
<dt>cluster</dt>
<dd>Metabolic cluster labels.</dd>
<dt>n_bins</dt>
<dd>Integer. Number of bins along mPT.</dd>
<dt>top_frac</dt>
<dd>Fraction of bins with highest composition change to define zone.</dd></dl>

Arguments

Identify candidate transition zone along mPT — scMetaTraj_transition_zone

<dl>

<dt>mPT</dt>
<dd>Numeric vector of metabolic pseudotime.</dd>


<dt>cluster</dt>
<dd>Metabolic cluster labels.</dd>


<dt>n_bins</dt>
<dd>Integer. Number of bins along mPT.</dd>


<dt>top_frac</dt>
<dd>Fraction of bins with highest composition change to define zone.</dd>

</dl>

scMetaTraj_transition_zone: Identify candidate transition zone along mPT

Description

Usage

Value

Arguments