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scaRabee (version 1.1-4)

dde.utils: Utility Functions for Delay Differential Equation Systems

Description

This is a collection of utility functions called by dde.model when a model defined by delay differential equations is evaluated. None of these functions is typically called directly by users.

Usage

dde.syst(t = NULL,
           y = NULL,
           ic = NULL,
           parms = NULL,
           derparms = NULL,
           delags = NULL,
           codedde = NULL,
           dosing = NULL,
           has.dosing = NULL,
           dose.states = NULL,
           xdata = NULL,
           covdata = NULL,
           scale = NULL,
           check = FALSE)
  dde.lags(parms = NULL,
           derparms = NULL,
           codelags = NULL,
           check = FALSE)

Arguments

t

A scalar or a vector of numerical time values.

y

A vector of system state values.

ic

A vector of initial conditions, typically returned by init.cond.

parms

A vector of primary parameters.

derparms

A list of derived parameters, specified in the $DERIVED block of code.

delags

A vector of delay parameters, typically returned by dde.lags.

codedde

The content of the R code specified within the $DDE block in the model file.

dosing

A data.frame of dosing information created by make.dosing from instantaneous and zero-order inputs into the system and containing the following columns:

TIME

Dosing event times.

CMT

State where the input should be assigned to.

AMT

Amount that should be assigned to system state at the corresponding TIME.

RATE

Rate of input that should be assigned to system CMT at the corresponding TIME. See vignette('scaRabee',package='scaRabee') for more details about the interpolation of the input rate at time not specified in dosing.

TYPE

An indicator of the type of input. TYPE is set to 1 if the record in dosing correspond an original bolus input; it is set to 0 otherwise.

has.dosing

A logical variable, indicating whether any input has to be assigned to a system state.

dose.states

A vector of integers, indicating in which system state one or more doses have to be assigned to.

xdata

A vector of times at which the system is being evaluated.

covdata

A matrix of covariate data extracted from the dataset.

scale

A vector of system scale, typically returned by input.scaling

check

An indicator whether checks should be performed to validate function inputs

codelags

The content of the R code specified within the $LAGS block in the model file.

Author

Sebastien Bihorel (sb.pmlab@gmail.com)

Details

dde.syst is the function which actually evaluates the system of delay differential equations specified in the $DDE block.

dde.lags is the function which evaluates the code specified in the $LAG block and defines the delays at which the system needs to be computed.

See Also

dde.model, make.dosing