weighting

parms

A list of derived parameters, specified in the $DERIVED block
 of code.

derparms

The content of the R code specified within the $VARIANCE block 
 in the model file.

codevar

The matrix of structural model predictions.

A vector of times at which the system is being evaluated.

xdata

An indicator whether checks should be performed to validate 
 function inputs

check

<code>weighting</code> is a secondary function called during estimation run to
 evaluate the model(s) of residual variability specified by the code provided
 in the $VARIANCE block. <code>weighting</code> is typically not called directly by
 users.

 method 

A port of the Scarabee toolkit originally written as a
Matlab-based application. scaRabee provides a framework for simulation and optimization
of pharmacokinetic-pharmacodynamic models at the individual and population level.
It is built on top of the neldermead package, which provides the direct search
algorithm proposed by Nelder and Mead for model optimization.

Sebastien Bihorel

scaRabee

Optimization Toolkit for Pharmacokinetic-Pharmacodynamic Models

weighting function

<dl> <dt>parms</dt>
<dd>A vector of primary parameters.</dd> <dt>derparms</dt>
<dd>A list of derived parameters, specified in the $DERIVED block
 of code.</dd> <dt>codevar</dt>
<dd>The content of the R code specified within the $VARIANCE block 
 in the model file.</dd> <dt>y</dt>
<dd>The matrix of structural model predictions.</dd> <dt>xdata</dt>
<dd>A vector of times at which the system is being evaluated.</dd> <dt>check</dt>
<dd>An indicator whether checks should be performed to validate 
 function inputs</dd></dl>

Arguments

Sebastien Bihorel (<a href="/link/sb.pmlab%40gmail.com?package=scaRabee&version=1.1-4" data-mini-rdoc="scaRabee::sb.pmlab@gmail.com">sb.pmlab@gmail.com</a>)

Author

Residual Variability — weighting

<dl>

 <dt>parms</dt>
<dd>A vector of primary parameters.</dd>

 <dt>derparms</dt>
<dd>A list of derived parameters, specified in the $DERIVED block
 of code.</dd>

 <dt>codevar</dt>
<dd>The content of the R code specified within the $VARIANCE block 
 in the model file.</dd>

 <dt>y</dt>
<dd>The matrix of structural model predictions.</dd>

 <dt>xdata</dt>
<dd>A vector of times at which the system is being evaluated.</dd>

 <dt>check</dt>
<dd>An indicator whether checks should be performed to validate 
 function inputs</dd>

</dl>

Sebastien Bihorel (<a href='mailto:sb.pmlab@gmail.com'>sb.pmlab@gmail.com</a>)

weighting: Residual Variability

Description

Usage

Value

Arguments

Author