coef_nnls

Computes non-negative least squares coefficients with a matrix
right hand side.

internal

Implementation of the scregclust algorithm
described in Larsson, Held, et al. (2024) <doi:10.1038/s41467-024-53954-3>
which reconstructs regulatory programs of target genes in scRNA-seq data.
Target genes are clustered into modules and each module is associated with a linear
model describing the regulatory program.

Felix Held

scregclust

Reconstructing the Regulatory Programs of Target Genes in
scRNA-Seq Data

Ida Larsson

Sven Nelander

André Armatowski

coef_nnls function

<dl><dt>x</dt>
<dd>Coefficient matrix (p x n matrix)</dd>
<dt>y</dt>
<dd>Right hand side (p x m matrix)</dd>
<dt>eps</dt>
<dd>Convergence tolerance</dd>
<dt>max_iter</dt>
<dd>Maximum number of iterations</dd></dl>

Arguments

Compute NNLS coefficients — coef_nnls

<dl>

<dt>x</dt>
<dd>Coefficient matrix (p x n matrix)</dd>


<dt>y</dt>
<dd>Right hand side (p x m matrix)</dd>


<dt>eps</dt>
<dd>Convergence tolerance</dd>


<dt>max_iter</dt>
<dd>Maximum number of iterations</dd>

</dl>

coef_nnls: Compute NNLS coefficients

Description

Usage

Value

Arguments

References