sdtmchecks (version 1.0.0)

check_cm_cmlat: Check if ocular concomitant medication has laterality missing or laterality field is populated but route is not eye-related.

Description

This check assesses CMCAT = "CONCOMITANT MEDICATIONS" and flags potential ocular records with missing/inconsistent route and laterality: for eye-related CMROUTE ('INTRAVITREAL', 'OPHTHALMIC', etc.), CMLAT is not populated -or- CMROUTE is not eye-related (i.e., not INTRAVITREAL, OPHTHALMIC, TOPICAL, etc.) but CMLAT is LEFT/RIGHT/BILATERAL.

Usage

check_cm_cmlat(CM, preproc = identity, ...)

Value

boolean value if check failed or passed with 'msg' attribute if the test failed

Arguments

CM

Concomitant Medications Dataset for Ophtho Study with variables USUBJID, CMCAT, CMLAT, CMDECOD, CMTRT, CMROUTE, CMSPID (if Present), CMSTDTC (if Present)

preproc

An optional company specific preprocessing script

...

Other arguments passed to methods

Author

Monarch Shah (HackR 2021 Team Eye)

See Also

Other OPHTH: check_ae_aelat(), check_cm_cmlat_prior_ocular(), check_oe_bcva_1m_late_early_tot(), check_oe_bcva_4m_late_early_tot(), check_oe_bcva_4m_vs_1m_req(), check_oe_bcva_tot_mismatch(), check_oe_sc_lat_count_fingers(), check_pr_prlat(), check_sc_dm_eligcrit(), check_sc_dm_seyeselc()

Examples

CM <- data.frame(
   USUBJID = 1:7,
   CMCAT = "CONCOMITANT MEDICATIONS",
   CMSTDTC = 1:7,
   CMLAT   = c("Left", "","Bilateral", "", "", "LEFT", ""),
   CMTRT  = c("A", "B", "A", "B", "A", "A", "B"),
   CMDECOD = c("A", "B", "A", "B", "A", "A", "B"),
   CMROUTE = c("","OPHTHALMIC","INTRAVITREAL","INTRAVITREAL",
               "opHTHALMIC", "INTRaOCULAr", "INTRaOCULAr"),
   CMSPID  = "FORMNAME-R:13/L:13XXXX",
   stringsAsFactors = FALSE)
check_cm_cmlat(CM,preproc=roche_derive_rave_row)

CM <- data.frame(
   USUBJID = 1:5,
   CMCAT = rep("CONCOMITANT MEDICATIONS",5),
   CMSTDTC = 1:5,
   CMLAT   = c("Left", "LEFT","Bilateral",
               "RIGHT", "RIgHT"),
   CMTRT  = c("A", "B", "A", "B", "A"),
   CMDECOD = c("A", "B", "A", "B", "A"),
   CMROUTE = c("","OPHTHALMIC","INTRAVITREAL",
               "INTRaOCULAr", "opHTHALMIC"),
   stringsAsFactors = FALSE)
check_cm_cmlat(CM)

CM <- data.frame(
   USUBJID = 1:5,
   CMCAT = "CONCOMITANT MEDICATIONS",
   CMSTDTC = 1:5,
   CMLAT   = c("Left", "LEFT","Bilateral", "RIGHT", "RIgHT"),
   CMTRT  = c("A", "B", "A", "B", "A"),
   CMDECOD = c("A", "B", "A", "B", "A"),
   #CMROUTE = c("","OPHTHALMIC","INTRAVITREAL","INTRaOCULAr", "opHTHALMIC"),
   stringsAsFactors = FALSE)
check_cm_cmlat(CM)