sdtmchecks (version 1.0.0)

check_qs_qsdtc_after_dd: Check for QS dates occurring after death date

Description

This check looks for QS dates that occur after death date

Usage

check_qs_qsdtc_after_dd(AE, DS, QS)

Value

boolean value if check failed or passed with 'msg' attribute if the test failed

Arguments

AE

Adverse Event SDTM dataset with variables USUBJID, AEDTHDTC, AESTDTC, AEDECOD, and AETERM

DS

DS Disposition SDTM dataset with variables USUBJID, DSSTDTC, DSDECOD, and DSTERM

QS

Questionnaire Test Findings SDTM dataset with variables USUBJID, QSDTC, QSCAT, and QSORRES

Author

Monarch Shah

Examples

AE <- data.frame(USUBJID = c(1,1,1,2,2,2),
                 AEDTHDTC = c("", "", "2016-01-01", "", "2016-01", "2016-01-01"),
                 AESTDTC = "2016-01-01",
                 AEDECOD = LETTERS[1:6],
                 AETERM = LETTERS[1:6],
                 stringsAsFactors = FALSE)

DS <- data.frame(USUBJID = c(1,1,1,2,2,2),
                 DSSTDTC = "2016-01-01",
                 DSDECOD = c("A", "B", "death", "AC", "BC", "death"),
                 DSTERM = letters[1:6],
                 stringsAsFactors = FALSE)

QS <- data.frame(USUBJID = c(1,1,1,2,2,2),
                 QSDTC   = c("2015-06-30", "2015-09-30", "2015-12-30",
                             "2015-06-30", "2015-09-30", "2015-12-30"),
                 QSCAT   = "A",
                 QSORRES =  LETTERS[1:6],
                 QSSTAT  = "",
                 VISIT  =  c("Week 1", "Week 12", "Week 24", "Week 1", "Week 12", "Week 24"),
                 QSSTRESC = LETTERS[1:6],
                 stringsAsFactors = FALSE)

check_qs_qsdtc_after_dd(AE, DS, QS)

QS$QSDTC[3:5] <- "2016-01-03"
check_qs_qsdtc_after_dd(AE, DS, QS)

QS$QSSTAT[3] <- "Not Done"
check_qs_qsdtc_after_dd(AE, DS, QS)

DS$DSSTDTC <- NULL
check_qs_qsdtc_after_dd(AE, DS, QS)

AE1 <- data.frame(USUBJID = 1,
                  AEDTHDTC = "",
                  AESTDTC = c("2015-11-01", "2016-02-01"),
                  AEDECOD = "Rash",
                  AETERM = "RASH",
                  stringsAsFactors = FALSE)

DS1 <- data.frame(USUBJID = 1,
                  DSSTDTC = "2016-01",
                  DSCAT = c("DISPOSITION EVENT", "OTHER"),
                  DSSCAT = c('STUDY COMPLETION/EARLY DISCONTINUATION', ''),
                  DSDECOD = "DEATH",
                  DSTERM = c("DEATH", "DEATH DUE TO PROGRESSIVE DISEASE"),
                  stringsAsFactors = FALSE)

QS1 <- data.frame(USUBJID = 1,
                  QSDTC   = c("2015-06-30", "2016-01-15", "2016-01-15"),
                  QSCAT   = rep("EQ-5D-5L"),
                  QSORRES = "1",
                  QSSTAT  = "",
                  VISIT  =  c("Week 1", "Week 12", "Week 12"),
                  QSSTRESC = "1",
                  stringsAsFactors = FALSE)

check_qs_qsdtc_after_dd(AE=AE1, DS=DS1, QS=QS1)

AE1$AEDTHDTC[1:2] <- "2015-07-01"
check_qs_qsdtc_after_dd(AE=AE1, DS=DS1, QS=QS1)