RSdata

The data are a subsample of 1000 observations from Riksstroke, the Swedish Stroke Register. The original data consisted
of over 50 000 patients with first time ischemic stroke during the years 2009-2012. The data are limited to patients over
the age of 44 and its purpose is to illustrate the functioning of the functions in the package.

datasets

We implement functions to estimate and perform sensitivity analysis to unobserved confounding of direct and indirect effects introduced in Lindmark, de Luna and Eriksson (2018) <doi:10.1002/sim.7620> and Lindmark (2022) <doi:10.1007/s10260-021-00611-4>. The estimation and sensitivity analysis are parametric, based on probit and/or linear regression models. Sensitivity analysis is implemented for unobserved confounding of the exposure-mediator, mediator-outcome and exposure-outcome relationships.

Anita Lindmark

sensmediation

Parametric Estimation and Sensitivity Analysis of Direct and
Indirect Effects

RSdata function

A data frame with 1000 observations on the following 5 variables.<dl>
 <dt><code>cf.3mo</code></dt>
<dd>Outcome: case fatality within 3 months after stroke, 1 = deceased, 0 = not deceased.</dd> <dt><code>lowered.consc</code></dt>
<dd>Mediator: level of consciousness upon arrival to hospital. 1 = lowered consciousness, 0 = fully alert.</dd> <dt><code>AF</code></dt>
<dd>Exposure: atrial fibrillation. Factor with levels, "1" = atrial fibrillation, "0" = no atrial fibrillation.</dd> <dt><code>age.cat</code></dt>
<dd>Age at time of stroke. Factor with levels, "45-69", "70-79", "80-89" and "90-".</dd> <dt><code>sex</code></dt>
<dd>Factor with levels, "1" = male, "0" = female</dd>
</dl>

Format

Example data for the functions in sensmediation — RSdata

A data frame with 1000 observations on the following 5 variables.<dl>
 <dt><code>cf.3mo</code></dt>
<dd>Outcome: case fatality within 3 months after stroke, 1 = deceased, 0 = not deceased.</dd>

 <dt><code>lowered.consc</code></dt>
<dd>Mediator: level of consciousness upon arrival to hospital. 1 = lowered consciousness, 0 = fully alert.</dd>

 <dt><code>AF</code></dt>
<dd>Exposure: atrial fibrillation. Factor with levels, "1" = atrial fibrillation, "0" = no atrial fibrillation.</dd>

 <dt><code>age.cat</code></dt>
<dd>Age at time of stroke. Factor with levels, "45-69", "70-79", "80-89" and "90-".</dd>

 <dt><code>sex</code></dt>
<dd>Factor with levels, "1" = male, "0" = female</dd>


</dl>

RSdata: Example data for the functions in sensmediation

Description

Usage

Arguments

Format

Examples