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sglr (version 0.7)

An R package for power and boundary calculations in pre-licensure vaccine trials using a sequential generalized likelihood ratio test

Description

Functions for computing power and boundaries for pre-licensure vaccine trials using the Generalized Likelihood Ratio tests proposed by Shih, Lai, Heyse and Chen

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Version

Install

install.packages('sglr')

Monthly Downloads

195

Version

0.7

License

GPL (>= 2)

Maintainer

Balasubramanian Narasimhan

Last Published

May 3rd, 2014

Functions in sglr (0.7)

computeBoundary

A function to compute the boundary of the decision region in terms of the number of adverse events (AEs) of interest, such as vaccine AEs.

plotBoundary

A function to plot the boundary of the decision region

sglrWebapp

A function to run a web application to compute boundaries and plotting the decision region

glrSearch

This function searches through a space of design boundaries (scalar values a and b) to find values that achieve close to specified type I and type II errors for the sequential generalized likelihood ratio test of p0 versus p1 (specified respectively as vector of length 2) in pre-licensure vaccine trials

sglr-package

An R package for power and boundary calculations in pre-licensure vaccine trials using a sequential generalized likelihood ratio test