Performs the Benjamini-Yekutieli FDR-controlling method for multiple hypothesis testing.
Usage
BY(u, alpha = 0.05)
Value
A list containing the following values:
Rejections
The number of effects declared by the BY procedure.
FDR
The estimated false discovery rate.
Adjusted.pvalues
The adjusted p-values.
data
The original p-values.
alpha
The specified significance level for the test.
call
The matched call.
Arguments
u
A (non-empty) numeric vector of p-values.
alpha
Numeric value. The significance level of the test.
Author
Irene Castro Conde and Jacobo de Uña Álvarez
Details
The function BY allows for the application of the Benjamini and Yekutieli (2001) false discovery rate controlling procedure under dependence assumptions.
The false discovery rate is estimated by the simple method proposed by: Dalmasso, Broet, Moreau (2005), by taking n=1 in their formula.
References
Benjamini Y and Yekutieli D (2001). The control of the false discovery rate in multiple testing under dependency. Annals of Statistics 29, 1165--1188.
Dalmasso C, Broet P and Moreau T (2005). A simple procedure for estimating the false discovery rate. Bioinformatics 21:660--668