MRS5NFModel


5-mer model of somatic hypermutation targeting based on analysis of replacement and
silent mutations in non-functional IgK from NP-immunized Mus musculus.


datasets

Provides a computational framework for Bayesian estimation of
antigen-driven selection in immunoglobulin (Ig) sequences, providing an
intuitive means of analyzing selection by quantifying the degree of
selective pressure. Also provides tools to profile mutations in Ig
sequences, build models of somatic hypermutation (SHM) in Ig sequences,
and make model-dependent distance comparisons of Ig repertoires.

Jason Vander Heiden

shazam

Immunoglobulin Somatic Hypermutation Analysis

MRS5NFModel function

<a rd-options="" href="/link/TargetingModel?package=shazam&version=0.1.4" data-mini-rdoc="shazam::TargetingModel">TargetingModel</a> object.

Format

<a rd-options='' href='TargetingModel'>TargetingModel</a> object.

MRS5NFModel: Mouse 5-mer targeting model.

Description

Usage

Arguments

Format

References

See Also