createRegionDefinition

<code>createRegionDefinition</code> creates a <code>RegionDefinition</code>.

Provides a computational framework for analyzing mutations in
immunoglobulin (Ig) sequences. Includes methods for Bayesian estimation of
antigen-driven selection pressure, mutational load quantification, building of
somatic hypermutation (SHM) models, and model-dependent distance calculations.
Also includes empirically derived models of SHM for both mice and humans.
Citations:
Gupta and Vander Heiden, et al (2015) <doi:10.1093/bioinformatics/btv359>,
Yaari, et al (2012) <doi:10.1093/nar/gks457>,
Yaari, et al (2013) <doi:10.3389/fimmu.2013.00358>,
Cui, et al (2016) <doi:10.4049/jimmunol.1502263>.

Susanna Marquez

shazam

Immunoglobulin Somatic Hypermutation Analysis

Mohamed Uduman

Namita Gupta

Julian Zhou

Nima Nouri

Noah Yann Lee

Ang Cui

Jason Vander Heiden

Gur Yaari

Steven Kleinstein

createRegionDefinition function

<dl><dt>name</dt>
<dd>name of the region definition.</dd>
<dt>boundaries</dt>
<dd><code>factor</code> defining the region boundaries of the sequence.
The levels and values of <code>boundaries</code> determine the 
number of regions (e.g. CDR and FWR).</dd>
<dt>description</dt>
<dd>description of the region definition and its source data.</dd>
<dt>citation</dt>
<dd>publication source.</dd></dl>

Arguments

Creates a RegionDefinition — createRegionDefinition

<dl>

<dt>name</dt>
<dd>name of the region definition.</dd>


<dt>boundaries</dt>
<dd><code>factor</code> defining the region boundaries of the sequence.
The levels and values of <code>boundaries</code> determine the 
number of regions (e.g. CDR and FWR).</dd>


<dt>description</dt>
<dd>description of the region definition and its source data.</dd>


<dt>citation</dt>
<dd>publication source.</dd>

</dl>

Creates a RegionDefinition

Last chance! 50% off unlimited learning

createRegionDefinition: Creates a RegionDefinition

Description

Usage

Value

Arguments

See Also

Examples