enrich_component_strand_bias

Genomic alterations including single nucleotide substitution,
copy number alteration, etc. are the major force for cancer
initialization and development. Due to the specificity of molecular
lesions caused by genomic alterations, we can generate characteristic
alteration spectra, called 'signature' (Wang, Shixiang, et al. (2021)
<DOI:10.1371/journal.pgen.1009557> & Alexandrov, Ludmil B., et al.
(2020) <DOI:10.1038/s41586-020-1943-3> & Steele Christopher D., et al.
(2022) <DOI:10.1038/s41586-022-04738-6>). This package helps users to
extract, analyze and visualize signatures from genomic alteration
records, thus providing new insight into cancer study.

Shixiang Wang

sigminer

Extract, Analyze and Visualize Mutational Signatures for Genomic
Variations

Ziyu Tao

Huimin Li

Tao Wu

Xue-Song Liu

Anand Mayakonda

enrich_component_strand_bias function

<dl><dt>mat</dt>
<dd>a sample-by-component matrix from sig_tally with strand bias labels "T:" and "B:".</dd></dl>

Arguments

Performs Strand Bias Enrichment Analysis for a Given Sample-by-Component Matrix — enrich_component_strand_bias

<dl>

<dt>mat</dt>
<dd>a sample-by-component matrix from sig_tally with strand bias labels "T:" and "B:".</dd>

</dl>

Performs Strand Bias Enrichment Analysis for a Given Sample-by-Component Matrix

enrich_component_strand_bias: Performs Strand Bias Enrichment Analysis for a Given Sample-by-Component Matrix

Description

Usage

Value

Arguments