simDNAmixtures (version 1.0.1)

sample_LSAE: Sample Locus Specific Amplification Efficiency (LSAE) according to prior

Description

Sample Locus Specific Amplification Efficiency (LSAE) according to prior

Usage

sample_LSAE(LSAE_variance, locus_names)

Value

Named numeric with LSAEs for each locus (names).

Arguments

LSAE_variance

Numeric. See gf for an example.

locus_names

Character vector.

Details

In the Bright et al. log normal model, the expected peak height includes a multiplicative factor for the locus (marker). These factors are called the LSAEs (Locus Specific Amplification Efficiencies). In the model, the prior for the log10 of LSAE is normal with mean 0. The variance can be specified.

Examples

data(gf)
lsae <- sample_LSAE(LSAE_variance = gf$log_normal_settings$LSAE_variance_prior,
                     locus_names = gf$autosomal_markers)

# the barplot shows that some loci amplify better than others
barplot(lsae, las=2)