get_site_mean_ae_dev

Internal function used by <code>site_aggr()</code>, <code>plot_visit_med75()</code>,
returns mean AE development from visit 0 to visit_med75.

Monitoring of Adverse Event (AE) reporting in clinical trials is
important for patient safety. Sites that are under-reporting AEs can be detected
using Bootstrap-based simulations that simulate overall AE reporting. Based on the
simulation an AE under-reporting probability is assigned to each site in a
given trial (Koneswarakantha 2021 <doi:10.1007/s40264-020-01011-5>).

Bjoern Koneswarakantha

simaerep

Find Clinical Trial Sites Under-Reporting Adverse Events

F. Hoffmann-La Roche Ltd 

get_site_mean_ae_dev function

<dl><dt>df_visit</dt>
<dd>dataframe</dd>
<dt>df_pat</dt>
<dd>dataframe as returned by pat_aggr()</dd>
<dt>df_site</dt>
<dd>dataframe as returned by site_aggr()</dd>
<dt>event_names</dt>
<dd>vector, contains the event names, default = "ae"</dd></dl>

Arguments

Get site mean ae development. — get_site_mean_ae_dev

<dl>

<dt>df_visit</dt>
<dd>dataframe</dd>


<dt>df_pat</dt>
<dd>dataframe as returned by pat_aggr()</dd>


<dt>df_site</dt>
<dd>dataframe as returned by site_aggr()</dd>


<dt>event_names</dt>
<dd>vector, contains the event names, default = "ae"</dd>

</dl>

get_site_mean_ae_dev: Get site mean ae development.

Description

Usage

Value

Arguments