sim_scenario

internal function called by simulate_scenarios()

Monitoring of Adverse Event (AE) reporting in clinical trials is
important for patient safety. Sites that are under-reporting AEs can be detected
using Bootstrap-based simulations that simulate overall AE reporting. Based on the
simulation an AE under-reporting probability is assigned to each site in a
given trial (Koneswarakantha 2021 <doi:10.1007/s40264-020-01011-5>).

Bjoern Koneswarakantha

simaerep

Find Clinical Trial Sites Under-Reporting Adverse Events

F. Hoffmann-La Roche Ltd 

sim_scenario function

<dl><dt>n_ae_site</dt>
<dd>integer vector</dd>
<dt>n_ae_study</dt>
<dd>integer vector</dd>
<dt>frac_pat_with_ur</dt>
<dd>double</dd>
<dt>ur_rate</dt>
<dd>double</dd></dl>

Arguments

simulate single scenario — sim_scenario

<dl>

<dt>n_ae_site</dt>
<dd>integer vector</dd>


<dt>n_ae_study</dt>
<dd>integer vector</dd>


<dt>frac_pat_with_ur</dt>
<dd>double</dd>


<dt>ur_rate</dt>
<dd>double</dd>

</dl>

sim_scenario: simulate single scenario

Description

Usage

Value

Arguments

Examples