sim_pat

<p>simulate patients and events for sites
supports constant and non-constant event rates</p>

internal

Monitoring reporting rates of subject-level clinical events (e.g.
adverse events, protocol deviations) reported by clinical trial sites is an
important aspect of risk-based quality monitoring strategy. Sites that are
under-reporting or over-reporting events can be detected using bootstrap
simulations during which patients are redistributed between sites. Site-specific
distributions of event reporting rates  are generated that are used to assign
probabilities to the observed reporting rates.
(Koneswarakantha 2024 <doi:10.1007/s43441-024-00631-8>).

Bjoern Koneswarakantha

simaerep

sim_pat: simulate patients and events for sites supports constant and non-constant event rates

Description

Usage

Arguments