simtrial (version 1.0.0)

maxcombo: MaxCombo test

Description

WARNING: This experimental function is a work-in-progress. The function arguments will change as we add additional features.

Usage

maxcombo(
  data = cut_data_by_event(sim_pw_surv(n = 200), 150),
  rho = c(0, 0, 1),
  gamma = c(0, 1, 1),
  return_variance = FALSE,
  return_corr = FALSE
)

Value

A list containing the test method (method), parameters of this test method (parameter), point estimate of the treatment effect (estimate), standardized error of the treatment effect (se), Z-score of each test of the MaxCombo (z), p-values (p_value) and the correlation matrix of each tests in MaxCombo (begin with v)

Arguments

data

A TTE dataset.

rho

Numeric vector. Must be greater than or equal to zero. Must be the same length as gamma.

gamma

Numeric vector. Must be greater than or equal to zero. Must be the same length as rho.

return_variance

A logical flag that, if TRUE, adds columns estimated variance for weighted sum of observed minus expected; see details; Default: FALSE.

return_corr

A logical flag that, if TRUE, adds columns estimated correlation for weighted sum of observed minus expected; see details; Default: FALSE.

See Also

wlr(), rmst(), milestone()

Examples

sim_pw_surv(n = 200) |>
  cut_data_by_event(150) |>
  maxcombo(rho = c(0, 0), gamma = c(0, 1), return_corr = TRUE)