snpEnrichment (version 1.6.0)

excludeSNP: Exclude SNPs from Enrichment analysis

Description

Remove a specify set of SNPs and compute a new enrichment analysis.

Usage

excludeSNP(object, excludeFile, mc.cores = 1)

Arguments

object

[Enrichment]: an Enrichment object filled by reSample.

excludeFile

[vector(character)]: a list of SNPs to remove from a previous enrichment analysis. A path to a file which the first column are the SNPs.

mc.cores

[numeric]: the number of cores to use (default is mc.cores=1), i.e. at most how many child processes will be run simultaneously. Must be at least one, and parallelization requires at least two cores.

Value

• Return the object given in argument where lists of SNPs are updated by removing SNPs in excludeFile.

See Also

Overview : snpEnrichment-package Classes : Enrichment, Chromosome, EnrichSNP Methods : plot, reSample, getEnrichSNP, excludeSNP, compareEnrichment, enrichment, is.enrichment, chromosome, is.chromosome Functions : initFiles, writeLD, readEnrichment

Examples

data(toyEnrichment)
excludeFile <- c(
    "rs4376885", "rs17690928", "rs6460708", "rs13061537", "rs11769827",
    "rs12717054", "rs2907627", "rs1380109", "rs7024214", "rs7711972",
    "rs9658282", "rs11750720", "rs1793268", "rs774568", "rs6921786",
    "rs1699031", "rs6994771", "rs16926670", "rs465612", "rs3012084",
    "rs354850", "rs12803455", "rs13384873", "rs4364668", "rs8181047",
    "rs2179993", "rs12049335", "rs6079926", "rs2175144", "rs11564427",
    "rs7786389", "rs7005565", "rs17423335", "rs12474102", "rs191314",
    "rs10513168", "rs1711437", "rs1992620", "rs283115", "rs10754563",
    "rs10851727", "rs2173191", "rs7661353", "rs1342113", "rs7042073",
    "rs1567445", "rs10120375", "rs550060", "rs3761218", "rs4512977"
)
# OR
excludeFile <- system.file("extdata/Exclude/toyExclude.txt",
                           package = "snpEnrichment")

toyEnrichment_exclude <- excludeSNP(toyEnrichment, excludeFile, mc.cores = 1)
toyEnrichment_exclude