bladTumor: Bladder Tumors Cancer Recurrences

Description

A data frame contains data on recurrences of bladder cancer, used by many people to demonstrate methodology for recurrent event modeling. The data was obtained by courtesy of Ying Zhang, containing records of 118 patients from three treatment arms: 48 are from the placebo arm, 37 are from the thiotepa arm, and the rest 33 are from the pyridoxine arm.

Usage

data(bladTumor)

Arguments

Format

A data.frame contains the following columns:

subject: patient id
time: observation time
count: cumulative number of tumors
count2: number of new tumors since last observation time
number: initial number of tumors (8=8 or more)
size: size (cm) of largest initial tumor
pyridoxine: dummy variable for pyridoxine arm
thiotepa: dummy variable for thiotepa arm

References

Byar, D. P. (1980). The Veterans administration study of chemoprophylaxis for recurrent stage I bladder tumors: Comparisons of placebo, pyridoxine, and topical thiotepa. Bladder Tumors and Other Topics in Urological Oncology, pp. 363--370. New York: Plenum.

Wellner, J. A. and Zhang, Y. (2007) Two likelihood-based semiparametric estimation methods for panel count data with covariates. Annals of Statistics, 35(5), 2106--2142.

Lu, M., Zhang, Y. and Huang, J. (2009) Semiparametric estimation methods for panel count data using monotone B-Splines. Journal of the American Statistical Association 104(487), 1060--1070.

Examples

Run this code

# NOT RUN {
data(bladTumor)
## Plot bladder tumor data
p <- plot(with(bladTumor, PanelSurv(subject, time, count2)))
print(p)
# }