ACTG175: AIDS Clinical Trials Group Study 175
Description
ACTG 175 was a randomized clinical trial to compare monotherapy with zidovudine or didanosine with
combination therapy with zidovudine and didanosine or zidovudine and zalcitabine in adults infected with the human
immunodeficiency virus type I whose CD4 cell counts were between 200 and 500 per cubic millimeter.Details
There are two treatment arms in the data set, zidovudine monotherapy and the mixture of all other study
therapies. The data set includes the following post-randomization covariates: CD4 and CD8 cell count at 20$\pm$5
weeks and the indicator of whether or not the patient was taken off-treatment before 96$\pm$5 weeks.References
Hammer SM, et al. (1996), "A trial comparing nucleoside monotherapy with combination therapy in
HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter.", New England Journal of Medicine,
335:1081--1090.