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speff2trial (version 1.0.4)

Semiparametric efficient estimation for a two-sample treatment effect

Description

The package performs estimation and testing of the treatment effect in a 2-group randomized clinical trial with a quantitative, dichotomous, or right-censored time-to-event endpoint. The method improves efficiency by leveraging baseline predictors of the endpoint. The inverse probability weighting technique of Robins, Rotnitzky, and Zhao (JASA, 1994) is used to provide unbiased estimation when the endpoint is missing at random.

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Version

Install

install.packages('speff2trial')

Monthly Downloads

412

Version

1.0.4

License

GPL-2

Maintainer

Michal Juraska

Last Published

October 30th, 2012

Functions in speff2trial (1.0.4)

ACTG175

AIDS Clinical Trials Group Study 175
summary.speff

Summarizing results for semiparametric efficient estimation and testing for a 2-sample treatment effect
speff

Semiparametric efficient estimation and testing for a two-sample treatment effect with a quantitative or dichotomous endpoint
modSearch

Internal function for speff()
speffSurv

Semiparametric efficient estimation and testing for a two-sample treatment effect with a right-censored time-to-event endpoint
summary.speffSurv

Summarizing results for semiparametric efficient estimation and testing for a two-sample treatment effect with a right-censored time-to-event endpoint