spls (version 1.0-0)

yeast: Yeast Cell Cycle Dataset

Description

This is the Yeast Cell Cycle dataset used in Chun and Keles (2007).

Usage

data(yeast)

source

Lee, T. I., N. J. Rinaldi, F. Robert, D. T. Odom, Z. Bar-Joseph, G. K. Gerber, N. M. Hannett, C. T. Harbison, C. M. Thomson, I. Simon, J. Zeitlinger, E. G. Jennings, H. L. Murray, D. B. Gordon, B. Ren, J. J. Wyrick, J.-B. Tagne, T. L. Volkert, E. Fraenkel, D. K. Gifford, and R. A. Young (2002). "Transcriptional regulatory networks in Saccharomyces cerevisiae", Science, 298, pp. 799--804. Spellman, P. T., G. Sherlock, M. Q. Zhang, V. R. Iyer, K. Anders, M. B. Eisen, P. O. Brown, D. Botstein, and B. Futcher (1998). "Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hydrization", Molecular Biology of the Cell, 9, pp. 3273--3279.

Details

The y matrix is the cell cycle gene expression data (Spellman et al., 1998) of 542 genes from an $\alpha$ factor based experiment. Each column corresponds to mRNA levels measured at every 7 minutes during 119 minutes (a total of 18 measurements). The x matrix is the chromatin immunoprecipitation on chip (ChIP-chip) data of Lee et al. (2002) and it contains the binding information for 106 transcription factors. See Chun and Keles (2007) for more details.

References

Chun, H. and Keles, S. (2007). "Sparse partial least squares for simultaneous dimension reduction and variable selection", (http://www.stat.wisc.edu/~keles/Papers/SPLS_Nov07.pdf).

Examples

data(yeast)
yeast$x[1:5,1:5]
yeast$y[1:5,1:5]