Seeds_Score

datasets

A systematic bioinformatics tool to perform single-sample mutation-based pathway analysis by integrating somatic mutation data with the Protein-Protein Interaction (PPI) network. In this method, we use local and global weighted strategies to evaluate the effects of network genes from mutations according to the network topology and then calculate the mutation-based pathway enrichment score (ssMutPES) to reflect the accumulated effect of mutations of each pathway. Subsequently, the ssMutPES profiles are used for unsupervised spectral clustering to identify cancer subtypes.

Junwei Han

ssMutPA

Single-Sample Mutation-Based Pathway Analysis

Yalan He

Qian Wang

Seeds_Score function

<p>An object of class <code>data.frame</code> with 35 rows and 2 columns.</p>

Format

Seeds_Score The local weight of seed nodes. — Seeds_Score

Seeds_Score The local weight of seed nodes.

Seeds_Score: Seeds_Score The local weight of seed nodes.

Description

Usage

Arguments

Format