rmCNVinVCF

cnvobj

<p>Remove CNV regions within VCF files given cnv file</p>

Imports Variant Calling Format file into R. It can detect
whether a sample contains contaminant from the same species.
In the first stage of the approach, a change-point detection
method is used to identify copy number variations for filtering.
Next, features are extracted from the data for a support vector
machine model. For log-likelihood calculation, the deviation
parameter is estimated by maximum likelihood method. Using
a radial basis function kernel support vector machine, the
contamination of a sample can be detected.

Tao Jiang

rmCNVinVCF: Remove CNV regions within VCF files given cnv file

Description

Usage

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