d2_nm_poppkpd

<p>this dataset was simulated by using theophylline population PK data and an indirect
response PD model.
Covariates <code>BMK1</code> and <code>BMK2</code> were randomly assigned.</p>

Expansion and additions to 'rstan' to facilitate pharmacokinetics (PK)
and pharmacodynamics (PD) modeling with 'rstan'.  A PKPD model often is specified
via a set of ordinary differential equations(ODEs) and requires flexible and
different routes of drug administrations.  These features make PKPD modeling
with plain 'rstan' challenging and tedious to code.  'stanette' provides a powerful
Stan-compatible ODE solver ('LSODA') and mechanism/utilities that make easy
specification of flexible dosing records.

Wenping Wang

stanette

R Interface to Stan

Yuan Xiong

Huijuan Xu

rstan developers

Trustees of Columbia University

John Plevyak

Linda Petzold

d2_nm_poppkpd function

simulated theophylline data — d2_nm_poppkpd

simulated theophylline data

d2_nm_poppkpd: simulated theophylline data

Description

Arguments