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sumFREGAT (version 1.0.0)

Fast Region-Based Association Tests on Summary Statistics

Description

An adaptation of classical region/gene-based association analysis techniques that uses summary statistics (P values and effect sizes) and correlations between genetic variants as input. It is a tool to perform the most common and efficient gene-based tests on the results of genome-wide association (meta-)analyses without having the original genotypes and phenotypes at hand.

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Version

Install

install.packages('sumFREGAT')

Monthly Downloads

269

Version

1.0.0

License

GPL-3

Maintainer

Nadezhda M Belonogova

Last Published

January 17th, 2018

Functions in sumFREGAT (1.0.0)

MLR

Multiple Linear Regression
PCA

Principal Components Analysis
BT

Family Burden Test
FLM

Functional Linear Model
sumFREGAT-package

sumFREGAT: Fast REGional Association Tests on summary statistics
SKAT

Sequence kernel association test
prep.score.files

Prepare score files