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superFreq (version 1.2.3)

getCosmicCounts: Retrieves information about cosmic variant IDs

Description

Retrieves information about cosmic variant IDs

Usage

getCosmicCounts(cosmic,
  cosmicDirectory = "/wehisan/general/academic/grp_leukemia_genomics/data/resources/COSMIC",
  onlyCensus = T, genome = "hg19")

Arguments

cosmic

character: The cosmic IDs.

cosmicDirectory

character: The directory where the cosmic files CosmicMutantExportCensus.tsv and CosmicMutantExport.tsv are located.

onlyCensus

logical: Restrict to cosmic census genes.

Details

For each cosmic ID, return whether it is seen in a census gene, and the mutations per million tumors (MPM) for that variant, as well as the average MPM over the gene (mutations per million tumors per basepair, MPMPB).