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survivalsurrogate (version 1.1)

Evaluate a Longitudinal Surrogate with a Censored Outcome

Description

Provides influence function-based methods to evaluate a longitudinal surrogate marker in a censored time-to-event outcome setting, with plug-in and targeted maximum likelihood estimation options. Details are described in: Agniel D and Parast L (2025). "Robust Evaluation of Longitudinal Surrogate Markers with Censored Data." Journal of the Royal Statistical Society: Series B . A tutorial for this package can be found at and a Shiny App implementing the package can be found at .

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Version

Install

install.packages('survivalsurrogate')

Monthly Downloads

166

Version

1.1

License

GPL

Maintainer

Layla Parast

Last Published

June 5th, 2025

Functions in survivalsurrogate (1.1)

plugin_delta

Treatment effect estimation using plug-in estimator
tmle_delta_s

Residual treatment effect estimation using TMLE
plugin_delta_s

Residual treatment effect estimation using the plug-in estimator
tmle_delta

Treatment effect estimation using TMLE
exampledata

Example dataset
estimate_R

Estimates the proportion of the treatment effect explained