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swCRTdesign (version 2.1)

swCRTdesign-package: Stepped Wedge Cluster Randomized Trial (SW CRT) Design

Description

This package includes functions for the design and analysis of stepped wedge cluster randomized trials according to a repeated cross-sectional sampling scheme. Four primary functions - swPwr, swSim, swSummary, and swPlot - and two support functions - blkDiag, swDsn - are included. The blkDiag function creates a block diagonal matrix from a specified array or list of block-matrices. The swDsn function creates a stepped wedge (SW) design object based on specified information on clusters, time points, and the two arms of the cluster randomized trial (CRT). The swPwr function computes the (two-sided) power of treatment effect ($\theta$) for the specified SW CRT design via weighted least squares (WLS), where the response/outcome of interest is assumed to come from a mixed effects model with(possibly correlated) random intercepts and random treatment effects. The swSim function generates individual-level data consisting of response, treatment, time, and cluster variables based on a specified SW CRT design. The swSummary function computes the mean, sum, or number of non-missing response values for clusters separately or aggregated by wave at each time point from stepped wedge data that includes, at least, response, treatment, time, and cluster variables. The swPlot function plots mean response as a combined or separate plot, for waves and clusters.

Arguments

Details

Package:
swCRTdesign
Type:
Package
Version:
2.1
Date:
2015-04-16
License:
GPL (>= 2)

References

Hussey MA, Hughes JP. Design and analysis of stepped wedge cluster randomized trials. Contemporary Clinical Trials 2007;28:182-191.