readmodel

contain the constraints matrix

list of metabolites

mets

list of reactions and their bounds

rxns

bounds of rows of constraint matrix

rbnds

bounds of columns of constraint matrix

cbnds

solver used to solve the lp, can be glpkAPI or cplexAPI

solver

create lp from lists generated from MATLAB MOMENT model.

Different techniques of cost constrained flux balance analysis.
1- MetabOlic Modeling with ENzyme kineTics 'MOMENT' which uses enzyme kinetic data and enzyme molecular
weights to constrain flux balance analysis(FBA) and it is described in Adadi, R., Volkmer, B., Milo, R.,
Heinemann, M., & Shlomi, T. (2012). Prediction of Microbial Growth Rate versus Biomass Yield by a Metabolic Network
with Kinetic Parameters, 8(7). <doi:10.1371/journal.pcbi.1002575>.
2- an improvement of 'MOMENT' that considers multi-functional enzymes 'ccFBA'.
Described in Desouki, Abdelmoneim. Algorithms for improving the predictive power of flux balance analysis. PhD dissertation, 2016.
FBA is a mathematical technique to find fluxes in metabolic models at steady state.
It is described in Orth, J.D., Thiele, I. and Palsson, B.O. What is flux balance analysis? Nat. Biotech. 28, 245-248(2010).

readmodel: read MOMENT model

Description

Usage

Arguments

Value

References

See Also