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tLagInterim (version 1.0)

Interim Monitoring of Clinical Trials with Time-Lagged Outcome

Description

Implements inverse and augmented inverse probability weighted estimators for common treatment effect parameters at an interim analysis with time-lagged outcome that may not be available for all enrolled subjects. Produces estimators, standard errors, and information that can be used to compute stopping boundaries using software that assumes that the estimators/test statistics have independent increments. Tsiatis, A. A. and Davidian, M., (2022) .

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Version

Install

install.packages('tLagInterim')

Monthly Downloads

524

Version

1.0

License

GPL-2

Maintainer

Shannon Holloway

Last Published

August 17th, 2022

Functions in tLagInterim (1.0)

print

Print results from a tLagInterim object
tLagIntBin

Toy Dataset With a Binary Outcome For Illustration
tLagIntCat

Toy Dataset With a Categorical Outcome For Illustration
tLagIntCont

Toy Dataset With a Continuous Outcome For Illustration
tLagInterim

Group Sequential Methods for Interim Monitoring of Randomized Clinical Trials with Time-lagged Outcome